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HEXAXIM
is a six-component vaccine against diphtheria, tetanus, whooping cough, hepatitis B, polio (inactivated) and hemophilic bacillus type
Suspension for injection, 0.5 ml (1 dose)
Manufacturer: Sanofi Pasteur SA, 2, Avenue PontPaster F-69007 Lyon France
Indications: Primary immunization and booster vaccination against:
  • Diphtheria
  • Tetanus
  • Whooping cough
  • Hepatitis B
  • Polio
  • Invasive infections caused by Haemophilus influenzae type b in newborns and children aged 6 weeks to 24 months of life.
How to use Hexaxim and dose:
  • Primary vaccination course. The primary vaccination course consists of three doses of 0.5 ml (1 dose), administered at 2, 3 and 4 months of life; or at 3, 4 and 5 months of life; or at 2, 4 and 6 months of life, so that the interval between subsequent doses is at least 4 weeks. In case a dose of hepatitis B vaccine has been administered at birth, Hexaxim® can be used as an additional vaccination against hepatitis B from 6 weeks of life. If a second dose of hepatitis B vaccine is required to be administered earlier than this age, then a monovalent hepatitis B vaccine may be used.
  • Revaccination. After a course of primary vaccination with Hexaxim®, booster vaccination against hepatitis B and infection caused by Haemophilus influenzae type b should be carried out in the second year of the child’s life or at least 6 months after the last dose of the primary vaccination course. Hexaxim® or any other vaccine containing a hepatitis B component, Haemophilus influenzae type b polysaccharide and poliovirus antigens may be used to complete the booster dose.
Before vaccination, a pediatrician must be examined!
  1. Before use, the vaccine must be shaken until a homogeneous whitish, cloudy suspension is obtained.
  2. The vaccine should only be administered intramuscularly.
  3. In infants under 2 years of age, the vaccine is recommended to be administered intramuscularly into the anterolateral region of the thigh, and in older children into the deltoid muscle of the shoulder.
Do not use Hexaxim:
  • anaphylactic reactions to previous vaccination with this vaccine – hypersensitivity reactions to any component of the vaccine or to any ingredients of the vaccine (glutaraldehyde, formaldehyde, neomycin, streptomycin and polymyxin B);
  • encephalopathy of unknown etiology, occurring within 7 days of previous administration of a vaccine containing a pertussis component (whole cell or acellular). In this case, vaccination with pertussis vaccine should be discontinued and the child vaccinated with diphtheria, tetanus, hepatitis B, polio and Haemophilus influenzae type b vaccine only
  • progressive neurological disorder or uncontrolled epilepsy
  • increase in body temperature above 37 oС or exacerbation of a chronic disease or acute infectious disease.
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